of circulating lipids at the sites of damaged vessel walls as a result of the effects of smoking and high blood pressure. These deposits partially occlude the artery, resulting in reduced blood flow to tissues. Also, in diabetic patient, there will be condition called angiopathy. When happened, it will cause abnormalities inside blood vessels and capillary due to injury to endothelial cells associated with neuropathy. This will lead to poor perfusion of tissues, especially wound base. When pressure is placed on the skin, the skin is damaged and is unable to be repaired due to the lack of blood perfusing the tissue.
WHERE DO AU USUALLY HAPPEN?
They are most common on distal ends of limbs. A special type of ischemic ulcer developing in duodenum after severe burns is called Curling's ulcer.
WHAT IS HAPPENING IN EARLY PHASE OF AU?
Most often, an AU develops following a minor injury that is slow to heal due to the poor blood supply to the wound. In severe arterial disease, spontaneous cell death may cause skin breakdown without a precipitating injury. Alternatively, cholesterol deposits lining the blood vessel walls may break off and become lodged in smaller vessels downstream, causing a sudden and complete blockage in flow; this process is called embolic occlusion
WHO ARE THE MOST COMMON TO GET AU?
Certain lifestyle factors and medical conditions have been associated with the development of AU. These include:
"Should I be worried if I got AU?"
WHAT ARE TREATMENT MODALITIES FOR AU?
The primary goal of the treatment of AU is to increase circulation to the area, either surgically or medically :
"In an open non-healing wound of AU, patient can opt for skin graft / skin substitute"
TIPS FOR PATIENT WITH AU
The following precautions can help minimize the risk of developing AU in at-risk patients and to minimize complications in patients already exhibiting symptoms: